BDBM50362879 CHEMBL1940905

SMILES Nc1c(F)c(NCCNc2ccccn2)c2OCCC3(CCC3)n3cc(C(O)=O)c(=O)c1c23

InChI Key InChIKey=FBGUGRUHZTVCSL-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50362879   

TargetGlycogen synthase kinase-3 beta(Human)
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50362879(CHEMBL1940905)
Affinity DataIC50: 36nMAssay Description:Inhibition of human recombinant GSK3-beta after 1 hr by KinaseGlo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50362879(CHEMBL1940905)
Affinity DataEC50:  3.20E+3nMAssay Description:Inhibition of GSK3-beta in human HepG2 cells assessed as incorporation of [3H]glucose into glycogen after 3 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed