BDBM50362881 CHEMBL1940907

SMILES CC1COc2c(NCCNc3ccccn3)c(F)c(N)c3c2n(cc(C(O)=O)c3=O)C11CCC1

InChI Key InChIKey=YJBDZDUXHXQAIZ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50362881   

TargetGlycogen synthase kinase-3 beta(Human)
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50362881(CHEMBL1940907)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant GSK3-beta after 1 hr by KinaseGlo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50362881(CHEMBL1940907)
Affinity DataEC50:  1.40E+3nMAssay Description:Inhibition of GSK3-beta in human HepG2 cells assessed as incorporation of [3H]glucose into glycogen after 3 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed