BDBM50362915 CHEMBL1945793

SMILES NC(=O)[C@H]1CC[C@H](CC1)n1c2nc(cnc2[nH]c1=O)-c1ccc(O)cc1

InChI Key InChIKey=VMUOUYGEVPPHDL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50362915   

TargetSerine/threonine-protein kinase mTOR(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50362915(CHEMBL1945793)
Affinity DataIC50: 179nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50362915(CHEMBL1945793)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of mTOR-mediated S6 phosphorylation in human PC3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50362915(CHEMBL1945793)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of mTOR-mediated Akt phosphorylation in human PC3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed