BDBM50362981 CHEMBL1945171

SMILES CN(C)CCCc1ccc(C)c(Nc2ncc3CC(=S)Nc4cc(Cl)ccc4-c3n2)c1

InChI Key InChIKey=IAIOBCSUUBVREO-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50362981   

TargetVascular endothelial growth factor receptor 2(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50362981(CHEMBL1945171)
Affinity DataIC50: 10nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK3(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50362981(CHEMBL1945171)
Affinity DataIC50: 18nMAssay Description:Inhibition of PLK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50362981(CHEMBL1945171)
Affinity DataIC50: 49nMAssay Description:Inhibition of PDGFRbMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50362981(CHEMBL1945171)
Affinity DataIC50: 160nMAssay Description:Inhibition of KITMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50362981(CHEMBL1945171)
Affinity DataIC50: 720nMAssay Description:Inhibition of FLT3More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50362981(CHEMBL1945171)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed