BDBM50363264 CHEMBL1944719

SMILES Fc1ccc2c(CN(c3cncnc3)c3cccc(Cl)c3)cc(=O)[nH]c2c1F

InChI Key InChIKey=PIIVPLCXXVONIY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50363264   

TargetNitric oxide synthase, inducible(Human)
Afraxis

Curated by ChEMBL
LigandPNGBDBM50363264(CHEMBL1944719)
Affinity DataIC50: 210nMAssay Description:Inhibition of human iNOS expressed in HEK293 cells assessed as NO production by 2,3-diaminonapthalene-based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Afraxis

Curated by ChEMBL
LigandPNGBDBM50363264(CHEMBL1944719)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human nNOS expressed in HEK293 cells assessed as NO production by 2,3-diaminonapthalene-based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Afraxis

Curated by ChEMBL
LigandPNGBDBM50363264(CHEMBL1944719)
Affinity DataIC50: 7.90E+4nMAssay Description:Inhibition of human eNOS expressed in HEK293 cells assessed as NO production by 2,3-diaminonapthalene-based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed