BDBM50363430 CHEMBL1944776

SMILES N[C@@H]1CC[C@@H](C[C@@H]1CS(=O)(=O)c1ccccc1)NC(=O)CNC(=O)c1cc(ccc1NC(=O)N1CCC1)C(F)(F)F

InChI Key InChIKey=FVIPKDVNUOEKRA-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50363430   

TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50363430(CHEMBL1944776)
Affinity DataIC50: 1.40nMAssay Description:Displacement of [125I]MCP-1 from CCR2 in human PMBCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50363430(CHEMBL1944776)
Affinity DataIC50: 6.60nMAssay Description:Displacement of [125I]MCP-1 from CCR2 in human THP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50363430(CHEMBL1944776)
Affinity DataIC50: 8nMAssay Description:Antagonist activity at CCR2 by monocyte transmigration assay in pesence of 0.1% BSAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50363430(CHEMBL1944776)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at CCR2 by monocyte transmigration assay in pesence of 0.5% BSAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50363430(CHEMBL1944776)
Affinity DataIC50: 7.30E+3nMAssay Description:Displacement of [125I]MIP-1beta from CCR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed