BDBM50363665 CHEMBL1944651

SMILES COc1ccc2cc(ccc2c1)S(=O)(=O)Nc1ccc(cc1)-c1cccc(c1)C(F)(F)F

InChI Key InChIKey=QPHYLDHPPSIADW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50363665   

TargetUrokinase-type plasminogen activator(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50363665(CHEMBL1944651)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of human uPA using pyroGlu-Gly-Arg-p-NA.HCl as substrate preincubated for 15 mins prior substrate addition measured for 10 mins by spectro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50363665(CHEMBL1944651)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of recombinant tPA using H-D-Ile-Pro-Arg-pNA.2HCl as substrate preincubated for 15 mins prior substrate addition measured for 10 mins by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed