BDBM50363882 CHEMBL1944838

SMILES Cn1c2ccn(CC(=O)Nc3ccc(cc3)C(F)(F)F)c2c(=O)n(C)c1=O

InChI Key InChIKey=XTJCMZFNEXELMO-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50363882   

TargetTransient receptor potential cation channel subfamily A member 1(Human)
University of Ferrara

Curated by ChEMBL

LigandBDBM50363882(CHEMBL1944838)Copy SMILESCopy InChI

Affinity DataIC50: 400nMAssay Description:Antagonist activity at human TRPA1 expressed in human IMR90 cells assessed as inhibition of acrolein-induced calcium influx after 40 mins by fluoresc...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/22/2012
Entry Details Article
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TargetTransient receptor potential cation channel subfamily A member 1(Rat)
University of Ferrara

Curated by ChEMBL

LigandBDBM50363882(CHEMBL1944838)Copy SMILESCopy InChI

Affinity DataIC50: 2.80E+3nMAssay Description:Antagonist activity at Sprague-Dawley rat TRPA1 expressed in rat DRG neurons assessed as inhibition of acrolein-induced calcium influx after 40 mins ...More data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/22/2012
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL