BDBM50363883 CHEMBL1946120

SMILES Cn1c2ccn(CC(=O)Nc3nc(cs3)-c3ccc(F)c(c3)C(F)(F)F)c2c(=O)n(C)c1=O

InChI Key InChIKey=DTXASEKLDRHEQO-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50363883   

TargetTransient receptor potential cation channel subfamily A member 1(Human)
University of Ferrara

Curated by ChEMBL

LigandBDBM50363883(CHEMBL1946120)Copy SMILESCopy InChI

Affinity DataIC50: 1.30E+3nMAssay Description:Antagonist activity at human TRPA1 expressed in human IMR90 cells assessed as inhibition of acrolein-induced calcium influx after 40 mins by fluoresc...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/22/2012
Entry Details Article
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TargetTransient receptor potential cation channel subfamily A member 1(Rat)
University of Ferrara

Curated by ChEMBL

LigandBDBM50363883(CHEMBL1946120)Copy SMILESCopy InChI

Affinity DataIC50: 1.30E+3nMAssay Description:Antagonist activity at Sprague-Dawley rat TRPA1 expressed in rat DRG neurons assessed as inhibition of acrolein-induced calcium influx after 40 mins ...More data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/22/2012
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL