BDBM50364369 CHEMBL1950296

SMILES Fc1ccc(Nc2nc3cnc(nc3n2C2CCCC2)C2CCOCC2)c(F)c1

InChI Key InChIKey=WHZAXCJJPMIQLO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50364369   

TargetMitogen-activated protein kinase 14(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50364369(CHEMBL1950296)
Affinity DataIC50: 230nMAssay Description:Inhibition of p38alpha using myelin basic protein as substrate preincubated for 15 mins prior ATP addition measured after 60 mins by scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50364369(CHEMBL1950296)
Affinity DataIC50: 900nMAssay Description:Inhibition of hexa-His-tagged JNK1 expressed in baculoviral system using GST-tagged c-Jun as substrate preincubated for 15 mins prior ATP addition me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed