BDBM50364379 CHEMBL1950290

SMILES CC(C)Nc1ncc2nc(Nc3c(F)cccc3F)n([C@@H]3CC[C@H](O)CC3)c2n1

InChI Key InChIKey=SFDUUFDVJHFBRB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50364379   

TargetMitogen-activated protein kinase 14(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50364379(CHEMBL1950290)
Affinity DataIC50: 910nMAssay Description:Inhibition of p38alpha using myelin basic protein as substrate preincubated for 15 mins prior ATP addition measured after 60 mins by scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Celgene

Curated by ChEMBL
LigandPNGBDBM50364379(CHEMBL1950290)
Affinity DataIC50: 160nMAssay Description:Inhibition of hexa-His-tagged JNK1 expressed in baculoviral system using GST-tagged c-Jun as substrate preincubated for 15 mins prior ATP addition me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed