BDBM50364410 CHEMBL1950480

SMILES Fc1ccccc1-c1nc2ccc(nc2s1)C1(CC1)c1ccccc1

InChI Key InChIKey=DCBBXRFSJCTLPY-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50364410   

TargetSphingosine 1-phosphate receptor 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50364410(CHEMBL1950480)
Affinity DataEC50:  45nMAssay Description:Agonist activity at eGFP-tagged human S1P1 receptor expressed in U2OS cells assessed as receptor internalization after 1 hr by Hoechst dye-based micr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50364410(CHEMBL1950480)
Affinity DataEC50: >2.50E+4nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO cells coexpressing chimeric Gq/i5 G-protein assessed as Ca2+ release by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed