BDBM50364536 CHEMBL1950879

SMILES CCCc1cc(n[nH]1)-c1ccc(Oc2ccc(CC(O)=O)cc2OC)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1

InChI Key InChIKey=QJTJQXIBBHMOBJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50364536   

TargetProstaglandin D2 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50364536(CHEMBL1950879)
Affinity DataIC50: 4nMAssay Description:Displacement of [3H]PGD2 from human DP receptor expressed in HEK293 cells by scintillation counting in presence of 0.5% BSAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50364536(CHEMBL1950879)
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cells by scintillation counting in presence of 0.5% BSAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50364536(CHEMBL1950879)
Affinity DataIC50: 8nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cells by scintillation counting in presence of 50% plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50364536(CHEMBL1950879)
Affinity DataIC50: 46nMAssay Description:Displacement of [3H]PGD2 from human DP receptor expressed in HEK293 cells by scintillation counting in presence of 0.5% BSAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed