BDBM50364857 CHEMBL1950171

SMILES CN1CC2CN(CC2C1)c1ccc2oc3ccccc3c(=O)c2c1

InChI Key InChIKey=WUJHMDPPANTBTQ-UHFFFAOYSA-N

Data  3 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50364857   

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50364857(CHEMBL1950171)
Affinity DataEC50:  2.20E+3nMAssay Description:Agonist activity at human recombinant alpha7 nAChR expressed in xenopus oocytes by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50364857(CHEMBL1950171)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human recombinant alpha4beta2 nAChR in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50364857(CHEMBL1950171)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]methyllylcaconitine from alpha7 nAChR in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50364857(CHEMBL1950171)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]MLA from rat alpha7 nAChRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50364857(CHEMBL1950171)
Affinity DataKi:  1.10E+3nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed