BDBM50365542 CHEMBL1957664

SMILES CCCNC(=O)c1nc(-c2nc(C)cs2)c([nH]1)-c1ccc2OCOc2c1

InChI Key InChIKey=JWVRZTZGKRAVED-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50365542   

TargetTGF-beta receptor type-1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50365542(CHEMBL1957664)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of human recombinant ALK5 activity in human A549 cells assessed as TGFbeta-induced smad2/3 phosphorylation after 2 hrs by fluorescence ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50365542(CHEMBL1957664)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant GST-fused ALK5 using TMB substrate after 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed