BDBM50365585 CHEMBL1957816

SMILES Fc1ccc(CCN2CCN(CC2)C(=O)c2cccn3ccnc23)c(F)c1

InChI Key InChIKey=USTBGZUJKCBYAR-UHFFFAOYSA-N

Data  2 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50365585   

Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50365585(CHEMBL1957816)
Affinity DataKi:  1.60nMAssay Description:Displacement of [125I]-DOI from recombinant human 5HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50365585(CHEMBL1957816)
Affinity DataKi:  524nMAssay Description:Displacement of [125I]-DOI from recombinant human 5HT2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50365585(CHEMBL1957816)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human ERG by patch-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50365585(CHEMBL1957816)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50365585(CHEMBL1957816)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of CYP219 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50365585(CHEMBL1957816)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50365585(CHEMBL1957816)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50365585(CHEMBL1957816)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed