BDBM50365864 CHEMBL1957840

SMILES Clc1cccc(Cn2ccn3c2nc(cc3=O)N2CCOCC2)c1Cl

InChI Key InChIKey=YGCPMTVIAJZRNZ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50365864   

LigandPNGBDBM50365864(CHEMBL1957840)
Affinity DataIC50: 13nMAssay Description:Inhibition of PI3Kbeta by time-resolved FRET displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365864(CHEMBL1957840)
Affinity DataIC50: 16nMAssay Description:Inhibition of PI3Kdelta by time-resolved FRET displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365864(CHEMBL1957840)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of PI3Kgamma by time-resolved FRET displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365864(CHEMBL1957840)
Affinity DataIC50: 110nMAssay Description:Inhibition of PI3Kbeta-mediated AKT SER473 phosphorylation in human MDA-MB-468 cells after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50365864(CHEMBL1957840)
Affinity DataIC50: 500nMAssay Description:Inhibition of PI3Kalpha by time-resolved FRET displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed