BDBM50366174 CHEMBL1957605

SMILES ONC(=O)[C@@H]1CS(=O)(=O)CN1S(=O)(=O)c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=VVEIZVKRPYJCPP-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50366174   

Target72 kDa type IV collagenase(Human)
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)

Curated by ChEMBL
LigandPNGBDBM50366174(CHEMBL1957605)
Affinity DataIC50: 53nMAssay Description:Inhibition of full length MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured after 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)

Curated by ChEMBL
LigandPNGBDBM50366174(CHEMBL1957605)
Affinity DataIC50: 100nMAssay Description:Inhibition of MMP8 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)

Curated by ChEMBL
LigandPNGBDBM50366174(CHEMBL1957605)
Affinity DataIC50: 480nMAssay Description:Inhibition of MMP9 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)

Curated by ChEMBL
LigandPNGBDBM50366174(CHEMBL1957605)
Affinity DataIC50: 500nMAssay Description:Inhibition of MMP12 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)

Curated by ChEMBL
LigandPNGBDBM50366174(CHEMBL1957605)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of MMP1 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)

Curated by ChEMBL
LigandPNGBDBM50366174(CHEMBL1957605)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of MMP14 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)

Curated by ChEMBL
LigandPNGBDBM50366174(CHEMBL1957605)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of MMP3 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed