BDBM50366204 CHEMBL1957602

SMILES ONC(=O)[C@@H]1CSCN1S(=O)(=O)c1ccc(Oc2ccc(Cl)cc2)cc1

InChI Key InChIKey=UCAJNLLYTGJPBY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50366204   

Target72 kDa type IV collagenase(Human)
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)

Curated by ChEMBL
LigandPNGBDBM50366204(CHEMBL1957602)
Affinity DataIC50: 13nMAssay Description:Inhibition of full length MMP2 using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured after 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)

Curated by ChEMBL
LigandPNGBDBM50366204(CHEMBL1957602)
Affinity DataIC50: 16nMAssay Description:Inhibition of MMP9 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)

Curated by ChEMBL
LigandPNGBDBM50366204(CHEMBL1957602)
Affinity DataIC50: 160nMAssay Description:Inhibition of MMP3 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Colosseum Combinatorial Chemistry Centre For Technology (C4T Scarl)

Curated by ChEMBL
LigandPNGBDBM50366204(CHEMBL1957602)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of MMP1 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate preincubated for 1 hr prior substrate addition measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed