BDBM50367418 CHEMBL1743952::Carvotroline hydrochloride

SMILES Fc1ccc2[nH]c3CCN(CCc4ccncc4)Cc3c2c1

InChI Key InChIKey=PMXOASNGMJAYTN-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50367418   

TargetD(2) dopamine receptor(Rat)
Wyeth Laboratories

Curated by ChEMBL
LigandPNGBDBM50367418(Carvotroline hydrochloride | CHEMBL1743952)
Affinity DataKi:  110nMAssay Description:In vitro Dopamine receptor D2 affinity by using [3H]spiperone as the radioligand in rat limbic system at 1 uM concentration of compound; value may ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Wyeth Laboratories

Curated by ChEMBL
LigandPNGBDBM50367418(Carvotroline hydrochloride | CHEMBL1743952)
Affinity DataKi:  211nMAssay Description:In vitro 5-hydroxytryptamine 2 receptor affinity by using [3H]spiperone as the radioligand in rat cortical tissue; value may range from 165 to 263More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed