BDBM50367657 CHEMBL1237328

SMILES Fc1ccc(cc1)[C@H]1C[C@H](N2CCN(CCN3CCNC3=O)CC2)c2cc(F)ccc12

InChI Key InChIKey=MYVPKBWFYFYMBK-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50367657   

TargetTransporter(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50367657(CHEMBL1237328)
Affinity DataIC50: 17nMAssay Description:In vitro inhibition of [3H]norepinephrine uptake in rat brain synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50367657(CHEMBL1237328)
Affinity DataIC50: 67nMAssay Description:In vitro inhibition of [3H]dopamine uptake in rat brain synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50367657(CHEMBL1237328)
Affinity DataIC50: 320nMAssay Description:Inhibition of [3H]spiperone binding to 5-hydroxytryptamine 2 receptor from rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
LigandPNGBDBM50367657(CHEMBL1237328)
Affinity DataIC50: 900nMAssay Description:Inhibition of [3H]prazosin binding to alpha-1 adrenergic receptor from rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50367657(CHEMBL1237328)
Affinity DataIC50: 2.20E+3nMAssay Description:In vitro inhibition of [3H]5-HT transporter uptake in rat brain synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50367657(CHEMBL1237328)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of [3H]spiperone binding to Dopamine receptor D2 from rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed