BDBM50367767 CHEMBL4160801

SMILES Cn1cc(cn1)-c1ccc(CN2CCC(CC2)Nc2ccc(cn2)C#N)cc1

InChI Key InChIKey=HGFPGDNHRXCJFV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50367767   

TargetCyclin-dependent kinase 12(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50367767(CHEMBL4160801)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of N-terminal FLAG-tagged human full-length CDK12 (1 to 1490 residues)/N-terminal His-tagged CycK (1 to 580 residues) expressed in Sf9 cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed