BDBM50367956 CHEMBL4164065

SMILES Cn1cc(cn1)-c1ccc(N[C@H]2CC[C@@H](CC2)Nc2ccc(cn2)C#N)cc1

InChI Key InChIKey=RYKSRXJRAKPITJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50367956   

TargetCyclin-dependent kinase 12(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50367956(CHEMBL4164065)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of N-terminal FLAG-tagged human full-length CDK12 (1 to 1490 residues)/N-terminal His-tagged CycK (1 to 580 residues) expressed in Sf9 cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50367956(CHEMBL4164065)
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of GST-tagged human CDK2/CCNA2 (04 to 103 residues) pre-incubated for 5 mins before addition of histone H1 substrate and [gamma-33P]ATP an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed