BDBM50368195 CHEMBL4175014

SMILES CCCOc1ccc(cc1)-c1cc(OCCN2CCc3cc(OC)c(OC)cc3C2)c2c(OC)cc(OC)cc2n1

InChI Key InChIKey=YXTIUOGLXGCFRY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50368195   

TargetQuinolone resistance protein NorA(Staphylococcus aureus)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50368195(CHEMBL4175014)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of NorA in Staphylococcus aureus SA-1199B expressing GrlA A116E mutant assessed as reduction in EtBr efflux incubated for 5 mins by fluore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50368195(CHEMBL4175014)
Affinity DataIC50: 420nMAssay Description:Inhibition of SARS-CoV-2 nsp13 helicase-associated activity using 5'- AGT CTT CTC CTG GTG CTC GAA CAG TGA CCy3-3', 5'- BHQ-2-GTC ACT GTT CGA GCA CCA ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50368195(CHEMBL4175014)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of SARS-CoV-2 nsp13 ATPase-associated activity using ATP as substrate incubated for 30 mins by Biomol Green Reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed