BDBM50368541 CHEMBL4171640

SMILES CCc1ccc(cc1C#Cc1cnc2ccccn12)C(=O)Nc1cc(CN2CCN(C)CC2)cc(c1)C(F)(F)F

InChI Key InChIKey=RZKBSKVRXHFGJG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50368541   

TargetTyrosine-protein kinase ABL1(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50368541(CHEMBL4171640)
Affinity DataIC50: 21nMAssay Description:Inhibition of Abl1 (unknown origin) incubated for 1 hr in presence of Tyrosine-2 peptide substrate by FRET based Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetDiscoidin domain-containing receptor 2(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50368541(CHEMBL4171640)
Affinity DataIC50: 10nMAssay Description:Inhibition of DDR2 (unknown origin) incubated for 1 hr using fluorescein-poly-GAT substrate by TR-FRET based LANCE ULTRA kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetEpithelial discoidin domain-containing receptor 1(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50368541(CHEMBL4171640)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of DDR1 (unknown origin) incubated for 1 hr using fluorescein-poly-GAT substrate by TR-FRET based LANCE ULTRA kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed