BDBM50369712 CHEMBL4162612

SMILES FC(F)c1nc2ccccc2n1-c1nc(nc(n1)N1CCN(Cc2cn(CCCC(=O)Nc3cccc4C(=O)N(C5CCC(=O)NC5=O)C(=O)c34)nn2)CC1)N1CCOCC1

InChI Key InChIKey=HUOBKLASHKHDNO-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50369712   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Tsinghua University

Curated by ChEMBL

LigandBDBM50369712(CHEMBL4162612)Copy SMILESCopy InChI

Affinity DataIC50: 90nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 1 hr by Kinase-Glo luminescent kinase assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/15/2020
Entry Details Article
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