BDBM50370513 CHEMBL4166079

SMILES Clc1c(oc2ncnc(NCCc3ccc(NC(=O)Nc4ccc(CN5CCCCC5)cc4)cc3)c12)-c1ccccc1

InChI Key InChIKey=PNJRNTPHIQUHQO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50370513   

TargetAurora kinase A(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50370513(CHEMBL4166079)
Affinity DataIC50: 451nMAssay Description:Inhibition of GST-tagged human recombinant Aurora A kinase domain (123 to 401 residues) expressed in Sf9 cells after 120 mins by kinase-glo luminesce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAurora kinase B(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50370513(CHEMBL4166079)
Affinity DataIC50: 946nMAssay Description:Inhibition of human recombinant full length Aurora-B (1 to 344 residues) expressed in Sf9 cells after 90 mins by kinase-glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed