BDBM50370571 CHEMBL4160064::US10954217, Example 00236

SMILES COc1cccc(c1)-c1ccc2CN(Cc3ccccc3)CCc2c1

InChI Key InChIKey=BDECJFBHDUVJRU-UHFFFAOYSA-N

Data  16 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50370571   

TargetD(4) dopamine receptor(Human)
University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50370571(CHEMBL4160064 | US10954217, Example 00236)
Affinity DataKi:  3.80nMAssay Description:Displacement of [3H]-N-methylspiperone from human dopamine D4 expressed in stable HEK cells after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University Of Texas

US Patent
LigandPNGBDBM50370571(CHEMBL4160064 | US10954217, Example 00236)
Affinity DataKi:  4.90nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50370571(CHEMBL4160064 | US10954217, Example 00236)
Affinity DataKi:  4.90nMAssay Description:Displacement of [3H]-Pentazocine from sigma1 receptor in guinea pig brain membrane by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Human)
University Of Texas

US Patent
LigandPNGBDBM50370571(CHEMBL4160064 | US10954217, Example 00236)
Affinity DataKi:  57nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2021
Entry Details
US Patent

TargetSigma intracellular receptor 2(Rat)
University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50370571(CHEMBL4160064 | US10954217, Example 00236)
Affinity DataKi:  57nMAssay Description:Displacement of [3H]-ditolylguanidine from sigma2 receptor in rat PC12 cells by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50370571(CHEMBL4160064 | US10954217, Example 00236)
Affinity DataKi:  65nMAssay Description:Displacement of [3H]-LSD from human 5-HT2B receptor expressed in stable HEK cells after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50370571(CHEMBL4160064 | US10954217, Example 00236)
Affinity DataKi:  175nMAssay Description:Displacement of [3H]-N-methylspiperone from human dopamine D3 expressed in HEKT cells after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50370571(CHEMBL4160064 | US10954217, Example 00236)
Affinity DataKi:  733nMAssay Description:Displacement of [3H]-WAY100635 from human 5-HT1A receptor expressed in stable CHO cells after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50370571(CHEMBL4160064 | US10954217, Example 00236)
Affinity DataKi:  1.07E+3nMAssay Description:Displacement of [3H]-Mesulergine from human 5-HT2C receptor expressed in HEKT cells after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50370571(CHEMBL4160064 | US10954217, Example 00236)
Affinity DataKi:  1.56E+3nMAssay Description:Displacement of [3H]-Win35428 from human DAT expressed in stable HEK cells after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50370571(CHEMBL4160064 | US10954217, Example 00236)
Affinity DataKi:  2.37E+3nMAssay Description:Displacement of [3H]-QNB/[3H]-NMS from human muscarinic M3 receptor expressed in stable CHO cells after 90 mins by microbeta scintillation counting m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Human)
University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50370571(CHEMBL4160064 | US10954217, Example 00236)
Affinity DataKi:  2.74E+3nMAssay Description:Displacement of [3H]-Prazosin from human adrenergic alpha1D receptor after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50370571(CHEMBL4160064 | US10954217, Example 00236)
Affinity DataKi:  3.13E+3nMAssay Description:Displacement of [3H]-Prazosin from human adrenergic alpha1A receptor after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50370571(CHEMBL4160064 | US10954217, Example 00236)
Affinity DataKi:  4.89E+3nMAssay Description:Displacement of [3H]-Prazosin from human adrenergic alpha1B receptor expressed in HEKT cells after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50370571(CHEMBL4160064 | US10954217, Example 00236)
Affinity DataKi:  6.82E+3nMAssay Description:Displacement of [3H]-QNB/[3H]-NMS from human muscarinic M2 receptor expressed in stable CHO cells after 90 mins by microbeta scintillation counting m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAlpha-2B adrenergic receptor(Human)
University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50370571(CHEMBL4160064 | US10954217, Example 00236)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-Rauwolscine from human adrenergic alpha2B receptor expressed in HEKT cells after 90 mins by microbeta scintillation counting met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed