BDBM50371473 CHEMBL239046

SMILES CCN(Cc1ccccc1)Cc1ccc(cc1)-c1cc2cc(OCCNC(=O)\C=C\c3cc(F)cc(F)c3)ccc2oc1=O

InChI Key InChIKey=OWHHSAFAYNBMOB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50371473   

TargetAcetylcholinesterase(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50371473(CHEMBL239046)
Affinity DataIC50: 7.20nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2018
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50371473(CHEMBL239046)
Affinity DataIC50: 99nMAssay Description:Inhibition of recombinant human BACE1 by spectrofluorometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2018
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50371473(CHEMBL239046)
Affinity DataIC50: 99nMAssay Description:Inhibition of human recombinant BACE1 by spectrofluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50371473(CHEMBL239046)
Affinity DataIC50: 7.16E+3nMAssay Description:Inhibition of human recombinant AChE by Ellman methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed