BDBM50371611 CHEMBL258819

SMILES Oc1c(O)c(cc(C(=O)c2ccc(Oc3ccccc3)cc2)c1O)C(=O)c1nc2ccccc2s1

InChI Key InChIKey=CYBLECRKSFPWGB-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50371611   

TargetApoptosis regulator Bcl-2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50371611(CHEMBL258819)
Affinity DataIC50: 170nMAssay Description:Inhibition of human Bcl-2 protein by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
LigandPNGBDBM50371611(CHEMBL258819)
Affinity DataIC50: 310nMAssay Description:Inhibition of human Mcl-1 protein by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
LigandPNGBDBM50371611(CHEMBL258819)
Affinity DataKi:  37nMAssay Description:Inhibition of human Mcl-1 protein by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
LigandPNGBDBM50371611(CHEMBL258819)
Affinity DataKi:  37nMAssay Description:Binding affinity to Mcl-1 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50371611(CHEMBL258819)
Affinity DataKi:  1.11E+3nMAssay Description:Binding affinity to human Bcl-xL protein by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed