BDBM50372782 CHEMBL402579

SMILES Cc1nc2ccccc2n1C1CCN(Cc2ccc(cc2)-c2nc3ncnc(N)c3cc2-c2ccccc2)CC1

InChI Key InChIKey=XZZVNLYLIJCASD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50372782   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50372782(CHEMBL402579)
Affinity DataIC50: 69nMAssay Description:Inhibition of human recombinant Akt1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50372782(CHEMBL402579)
Affinity DataIC50: 221nMAssay Description:Inhibition of Akt1 phosphorylation in human C33a cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50372782(CHEMBL402579)
Affinity DataIC50: 281nMAssay Description:Inhibition of human recombinant Akt2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50372782(CHEMBL402579)
Affinity DataIC50: 344nMAssay Description:Inhibition of Akt2 phosphorylation in human C33a cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed