BDBM50372909 CHEMBL255421

SMILES COc1ccc(C=C2SC(O)=NC2=O)cc1OC

InChI Key InChIKey=ARJGUVIAPHIKLE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50372909   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
University of Paisley

Curated by ChEMBL
LigandPNGBDBM50372909(CHEMBL255421)
Affinity DataIC50: 1.41E+4nMAssay Description:Inhibition of PDE4BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50372909(CHEMBL255421)
Affinity DataIC50: 950nMAssay Description:Inhibition of human PIM1 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 50 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50372909(CHEMBL255421)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human PIM2 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 50 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50372909(CHEMBL255421)
Affinity DataIC50: 280nMAssay Description:Inhibition of human PIM3 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 50 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed