BDBM50372932 CHEMBL256894

SMILES Fc1ccc(cc1)-n1ncc2C[C@]3(CN4CCCC4)CN(CCC3=Cc12)S(=O)(=O)c1ccccc1

InChI Key InChIKey=JUBJYIBDDUCCTO-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50372932   

TargetGlucocorticoid receptor(Human)
Corcept Therapeutics

Curated by ChEMBL
LigandPNGBDBM50372932(CHEMBL256894)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]dexamethasone from human recombinant GRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Corcept Therapeutics

Curated by ChEMBL
LigandPNGBDBM50372932(CHEMBL256894)
Affinity DataKi:  4.90nMAssay Description:Antagonist activity at GR in SW1353/MMTV5 cells assessed as inhibition of dexamethasone-induced luciferase expressionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed