BDBM50373357 CHEMBL256092

SMILES CC(C)OC(=O)Nc1cc(C)n(Cc2cc(Cl)ccc2OCc2ccccc2)n1

InChI Key InChIKey=CKCKWQLHSQKPAK-UHFFFAOYSA-N

Data  4 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50373357   

TargetProstaglandin E2 receptor EP1 subtype(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50373357(CHEMBL256092)
Affinity DataKd:  7.94nMAssay Description:Antagonist activity at PGE2-EP1 receptor assessed as PGE2-induced response by schild analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50373357(CHEMBL256092)
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50373357(CHEMBL256092)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50373357(CHEMBL256092)
Affinity DataIC50: 6.90E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50373357(CHEMBL256092)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed