BDBM50373459 CHEMBL258696

SMILES CCN(CC)CCNC(=O)c1ccc2nc(-c3ccccc3)c(nc2c1)-c1ccc(CN2CCC(CC2)n2c3ccccc3[nH]c2=O)cc1

InChI Key InChIKey=HBCHTLGWXPVWDF-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50373459   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50373459(CHEMBL258696)
Affinity DataIC50: 527nMAssay Description:Inhibition of Akt1 by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50373459(CHEMBL258696)
Affinity DataIC50: 730nMAssay Description:Inhibition of Akt2 by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50373459(CHEMBL258696)
Affinity DataIC50: 138nMAssay Description:Inhibition of Akt1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50373459(CHEMBL258696)
Affinity DataIC50: 212nMAssay Description:Inhibition of Akt2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50373459(CHEMBL258696)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of Akt3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50373459(CHEMBL258696)
Affinity DataIC50: 138nMAssay Description:Inhibition of Akt1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50373459(CHEMBL258696)
Affinity DataIC50: 212nMAssay Description:Inhibition of Akt2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50373459(CHEMBL258696)
Affinity DataIC50: 253nMAssay Description:Inhibition of Akt1 by cell-based IPKA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50373459(CHEMBL258696)
Affinity DataIC50: 276nMAssay Description:Inhibition of Akt2 by cell-based IPKA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50373459(CHEMBL258696)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Akt3 by cell-based IPKA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50373459(CHEMBL258696)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of SGKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed