BDBM50374520 CHEMBL270444

SMILES CCN(CC)CCNC(=O)c1ccc2nc(-c3ccc(CN4CCC(CC4)n4c5ccccc5[nH]c4=O)cc3)c(nc2c1)-c1ccccc1

InChI Key InChIKey=PKOLTBBFTJODIG-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50374520   

LigandPNGBDBM50374520(CHEMBL270444)
Affinity DataIC50: 359nMAssay Description:Inhibition of Akt2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50374520(CHEMBL270444)
Affinity DataIC50: 368nMAssay Description:Inhibition of Akt1 by cell-based IPKA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50374520(CHEMBL270444)
Affinity DataIC50: 458nMAssay Description:Inhibition of Akt1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50374520(CHEMBL270444)
Affinity DataIC50: 617nMAssay Description:Inhibition of Akt2 by cell-based IPKA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50374520(CHEMBL270444)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of Akt3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
LigandPNGBDBM50374520(CHEMBL270444)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of Akt3 by cell-based IPKA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50374520(CHEMBL270444)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of SGKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed