BDBM50375488 CHEMBL260396

SMILES O=C(Nc1nc(nc(-c2ccc3OCOc3c2)c1C#N)-c1ccccc1)C1CCCC1

InChI Key InChIKey=QFNSOUDLGDVTFA-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50375488   

TargetAdenosine receptor A1(Human)
Leiden/Amsterdam Center For Drug Research

Curated by ChEMBL
LigandPNGBDBM50375488(CHEMBL260396)
Affinity DataIC50: 1.40E+3nMAssay Description:Activity at human adenosine A1 receptor expressed in CHO cells assessed as inhibition of CPA-induced decrease in forskolin-stimulated cAMP production...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Leiden/Amsterdam Center For Drug Research

Curated by ChEMBL
LigandPNGBDBM50375488(CHEMBL260396)
Affinity DataKi:  5.70nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Leiden/Amsterdam Center For Drug Research

Curated by ChEMBL
LigandPNGBDBM50375488(CHEMBL260396)
Affinity DataKi:  5.70nMAssay Description:Displacement of [3H]DPCPX from A1 adenosine receptor (unknown origin) expressed in CHO cell membrane incubated for 60 mins at room temperature by NXT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed