BDBM50375590 CHEMBL1552

SMILES C[C@H](CCC(=O)NCC(=O)O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2C(C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)C

InChI Key InChIKey=GHCZAUBVMUEKKP-UHFFFAOYSA-N

Data  1 KI  2 EC50

PDB links: 15 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50375590   

TargetBile acid receptor(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50375590(CHEMBL1552)
Affinity DataEC50:  3.00E+3nMAssay Description:Binding affinity for Farnesoid X Receptor (FXR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Centre National de la Recherche Scientifique/INSERM/ULP

Curated by ChEMBL
LigandPNGBDBM50375590(CHEMBL1552)
Affinity DataEC50:  3.88E+3nMAssay Description:Agonist activity at human TGR5 expressed in CHO cells by luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetBile salt export pump(Human)
King'S College Hospital

Curated by ChEMBL
LigandPNGBDBM50375590(CHEMBL1552)
Affinity DataKi:  7.00E+3nMAssay Description:TP_TRANSPORTER: competitive inhibition of Taurocholate uptake in membrane vesicles prepared from High Five cells infected with the ABCB11 baculovirusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed