BDBM50375606 CHEMBL76084

SMILES Cc1cccc(Cl)c1Nc1ccccc1CC(O)=O

InChI Key InChIKey=PQOGEFXKUUCLAX-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50375606   

TargetProstaglandin G/H synthase 2(Human)
Vanderbilt Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50375606(CHEMBL76084)
Affinity DataIC50: 20nMAssay Description:Inhibition of human COX2 for 17 mins pre-incubated before addition of [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Vanderbilt Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50375606(CHEMBL76084)
Affinity DataIC50: 58nMAssay Description:Inhibition of ovine COX1 for 17 mins pre-incubated before addition of [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Vanderbilt Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50375606(CHEMBL76084)
Affinity DataIC50: 35nMAssay Description:Inhibition of mouse COX2 for 17 mins pre-incubated before addition of [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Vanderbilt Institute For Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50375606(CHEMBL76084)
Affinity DataIC50: 35nMAssay Description:Inhibition of mouse COX2 for 20 mins pre-incubated before addition of [1-14C]arachidonic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1/2(Bovine)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50375606(CHEMBL76084)
Affinity DataIC50: 1.00E+9nMAssay Description:In vitro inhibition of bovine prostaglandin G/H synthase, using bovine seminal vesicle microsomal preparations; IC50 in umol/LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2019
Entry Details Article
PubMed