BDBM50376354 CHEMBL263374

SMILES Nc1ncnc2NCCC(=Nc12)c1cccc(NC(=O)Nc2ccccc2)c1

InChI Key InChIKey=NTRQSBNWMYCCJY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50376354   

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50376354(CHEMBL263374)
Affinity DataIC50: 888nMAssay Description:Inhibition of KDR in presence of 1 mM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50376354(CHEMBL263374)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of Flt3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50376354(CHEMBL263374)
Affinity DataIC50: 3.02E+3nMAssay Description:Inhibition of cKitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed