BDBM50376361 CHEMBL260848

SMILES Nc1ncnc2NCCC(=Nc12)c1cccc(NC(=O)Nc2cccc(c2)C(F)(F)F)c1

InChI Key InChIKey=UQCJNMPNMQFILJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50376361   

TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50376361(CHEMBL260848)
Affinity DataIC50: 91nMAssay Description:Inhibition of cKitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50376361(CHEMBL260848)
Affinity DataIC50: 126nMAssay Description:Inhibition of KDR in presence of 1 mM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50376361(CHEMBL260848)
Affinity DataIC50: 145nMAssay Description:Inhibition of Flt3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Mouse)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50376361(CHEMBL260848)
Affinity DataIC50: 790nMAssay Description:Inhibition of VEGF-induced KDR phosphorylation in mouse 3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed