BDBM50377660 CHEMBL255904

SMILES CC(C)Cn1nnc(Cc2ccc(cc2)-c2ccccc2)n1

InChI Key InChIKey=PPXBPBABGOMYLY-UHFFFAOYSA-N

Data  2 KI  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50377660   

TargetCannabinoid receptor 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50377660(CHEMBL255904)
Affinity DataKi:  1.60E+3nMAssay Description:Binding affinity to human CB1 receptor expressed in COS cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50377660(CHEMBL255904)
Affinity DataKi:  4.70E+3nMAssay Description:Binding affinity to human CB2 receptor expressed in COS cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50377660(CHEMBL255904)
Affinity DataEC50:  1.00E+4nMAssay Description:Agonist activity at human TRPV1 channel expressed in human HEK293 cells assessed as elevation in intracellular calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50377660(CHEMBL255904)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human DAGLalpha mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG in COS cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily A member 1(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50377660(CHEMBL255904)
Affinity DataEC50:  2.63E+4nMAssay Description:Agonist activity at rat TRPA1 channel expressed in human HEK293 cells assessed as elevation in intracellular calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50377660(CHEMBL255904)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of rat brain FAAH mediated [14C]anandamide hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed