BDBM50378628 CHEMBL599417::US8637558, 21

SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCCN2CCS(=O)(=O)CC2)cc1

InChI Key InChIKey=MTHLYVCSILZKES-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50378628   

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Chosun University

Curated by ChEMBL
LigandPNGBDBM50378628(CHEMBL599417 | US8637558, 21)
Affinity DataIC50: 1.96E+3nMAssay Description:Inhibition of human 15PGDH expressed in Escherichia coli BL-21 by fluorescence spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Chosun University

Curated by ChEMBL
LigandPNGBDBM50378628(CHEMBL599417 | US8637558, 21)
Affinity DataIC50: 3.04E+3nMpH: 7.5Assay Description:Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2014
Entry Details
US Patent