BDBM50378678 CHEMBL590542

SMILES CCOC(=O)c1sc(nc1C)N1C(c2c(oc3ccc(F)cc3c2=O)C1=O)c1ccc(C)cc1

InChI Key InChIKey=LXAKQLULUBLGTI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50378678   

TargetTyrosyl-DNA phosphodiesterase 1(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50378678(CHEMBL590542)
Affinity DataIC50: 4.47E+4nMAssay Description:Inhibition of human tyrosyl-DNA phosphodiesterase 1 after 30 mins by alpha high throughput screening assay in presence of 0.01% Tween-20More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
National Cancer Institute-Frederick

Curated by ChEMBL
LigandPNGBDBM50378678(CHEMBL590542)
Affinity DataIC50: 5.01E+4nMAssay Description:Inhibition of human tyrosyl-DNA phosphodiesterase 1 after 30 mins by alpha high throughput screening assay in presence of 0.05% Tween-20More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed