BDBM50378889 CHEMBL1743605

SMILES CN(C)[C@@H](Cc1c(C)cc(O)cc1C)C(=O)N1Cc2ccccc2C[C@H]1C(=O)NCCC(=O)OC1=C2O[C@H]3[C@@H](O)C=C[C@H]4[C@H]5CC(C=C1)C2[C@@]34CCN5C

InChI Key InChIKey=RYHSGCXJLCXQNY-UHFFFAOYSA-N

Data  3 KI  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50378889   

TargetDelta-type opioid receptor(Human)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50378889(CHEMBL1743605)
Affinity DataIC50: 0.810nMAssay Description:Antagonist activity at human delta opioid receptor expressed in CHO cells assessed as inhibition of U50488-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50378889(CHEMBL1743605)
Affinity DataEC50:  29nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50378889(CHEMBL1743605)
Affinity DataEC50:  20nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50378889(CHEMBL1743605)
Affinity DataIC50: 450nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50378889(CHEMBL1743605)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50378889(CHEMBL1743605)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50378889(CHEMBL1743605)
Affinity DataKi:  3.5nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed