BDBM50378890 CHEMBL1743604

SMILES CN(C)[C@@H](Cc1c(C)cc(O)cc1C)C(=O)N1Cc2ccccc2C[C@H]1C(=O)OC1=C2O[C@H]3[C@@H](O)C=C[C@H]4[C@H]5CC(C=C1)C2[C@@]34CCN5C

InChI Key InChIKey=XCSVQYRKBHKRNV-UHFFFAOYSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50378890   

TargetDelta-type opioid receptor(Human)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50378890(CHEMBL1743604)
Affinity DataIC50: 1.70nMAssay Description:Antagonist activity at human delta opioid receptor expressed in CHO cells assessed as inhibition of U50488-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50378890(CHEMBL1743604)
Affinity DataIC50: 3.10E+3nMAssay Description:Antagonist activity at human kappa opioid receptor expressed in CHO cells assessed as inhibition of SNC80-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50378890(CHEMBL1743604)
Affinity DataIC50: 13nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50378890(CHEMBL1743604)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50378890(CHEMBL1743604)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50378890(CHEMBL1743604)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed