BDBM50379219 CHEMBL2011303::US9416123, 19

SMILES Nc1cc(nn1-c1c(Cl)cc(Cl)cc1Cl)-c1ccncc1

InChI Key InChIKey=VCCMPDALPAMAII-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50379219   

TargetVascular endothelial growth factor receptor 2(Human)
Islamic University of Gaza

Curated by ChEMBL
LigandPNGBDBM50379219(CHEMBL2011303 | US9416123, 19)
Affinity DataIC50: 8.70E+4nMAssay Description:Inhibition of VEGFR2 using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Islamic University of Gaza

Curated by ChEMBL
LigandPNGBDBM50379219(CHEMBL2011303 | US9416123, 19)
Affinity DataIC50: 8.70E+4nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Islamic University of Gaza

Curated by ChEMBL
LigandPNGBDBM50379219(CHEMBL2011303 | US9416123, 19)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of SRC using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Islamic University of Gaza

Curated by ChEMBL
LigandPNGBDBM50379219(CHEMBL2011303 | US9416123, 19)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent

LigandPNGBDBM50379219(CHEMBL2011303 | US9416123, 19)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
US Patent