BDBM50379518 CHEMBL2012571

SMILES COc1ccc2c3ccnc(C)c3n(CCCCN)c2c1Cl

InChI Key InChIKey=LORKEEHZMNRSDL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50379518   

TargetSerine/threonine-protein kinase haspin(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50379518(CHEMBL2012571)
Affinity DataIC50: 830nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50379518(CHEMBL2012571)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of human N-terminal GST-tagged DYRK2 expressed in baculovirus using DYRKtide-F as substrate assessed as inhibition of [33P] incorporation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed