BDBM50379521 CHEMBL2012574

SMILES COc1ccc2c3ccnc(c3n(c2c1)CCCCN)C(F)(F)F

InChI Key InChIKey=JVBWXORXTBDUMH-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50379521   

TargetSerine/threonine-protein kinase haspin(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50379521(CHEMBL2012574)
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50379521(CHEMBL2012574)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human N-terminal GST-tagged DYRK2 expressed in baculovirus using DYRKtide-F as substrate assessed as inhibition of [33P] incorporation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed