BDBM50379530 CHEMBL2012701

SMILES CCc1[nH]nc2ncnc(N3CCN(CC3)c3cc(Cl)cc(NCCN(C)C)c3C)c12

InChI Key InChIKey=ACXREQVXILYMKB-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50379530   

TargetRibosomal protein S6 kinase alpha-3(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50379530(CHEMBL2012701)
Affinity DataIC50: 68nMAssay Description:Inhibition of Rsk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50379530(CHEMBL2012701)
Affinity DataIC50: 371nMAssay Description:Inhibition of Akt1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50379530(CHEMBL2012701)
Affinity DataIC50: 3.02E+3nMAssay Description:Inhibition of Akt2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50379530(CHEMBL2012701)
Affinity DataIC50: 371nMAssay Description:Inhibition of AKT1 after 3 hrs by luciferase based chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50379530(CHEMBL2012701)
Affinity DataIC50: 45nMAssay Description:Inhibition of p70S6K-mediated ribosomal protein S6 phosphorylation in human A549 cells after 3 hrs by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50379530(CHEMBL2012701)
Affinity DataIC50: 211nMAssay Description:Inhibition of p70S6K-mediated ribosomal protein S6 phosphorylation in human PC3 cells after 3 hrs by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50379530(CHEMBL2012701)
Affinity DataIC50: 9.03E+3nMAssay Description:Inhibition of AKT1-mediated GSK3beta phosphorylation in human PC3 cells after 3 hrs by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50379530(CHEMBL2012701)
Affinity DataIC50: 2nMAssay Description:Inhibition of p70S6K after 3 hrs by luciferase based chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed